How do age-related changes affect medication administration in older adults?

The correct answer highlights that age-related changes significantly influence medication administration in older adults due to alterations in metabolism, absorption, and organ function. As individuals age, physiological changes such as decreased liver and kidney function, changes in gastrointestinal tract function, and variations in body composition can affect how medications are processed in the body.

Metabolism may slow down, leading to prolonged drug action and increased potential for toxicity. Absorption can be altered, which affects how much of a medication reaches systemic circulation. Additionally, diminished kidney function can impair the excretion of drugs, necessitating careful monitoring and dosage adjustments to maintain efficacy while minimizing adverse effects.

Understanding these changes is crucial for healthcare providers to optimize medication therapy, ensuring that it is both effective and safe for older patients. This consideration allows for more personalized medication management, taking into account the unique health status and needs of the elderly population.